Malignant peripheral nerve sheath tumor is a rare sarcoma with ecto-mesenchymal origin. Intraosseous origin of MPNST is very rare and it can be associated with neurofibromatosis type 1 with an incidence of 5-42% in such patients. MPNSTs have rarely been reported in unusual body parts like head, neck and bone. Here we report a rare occurrence of MPNST in the right index finger where the tumor was found to arise from the soft tissue of index finger, involving the underlying bone.
Key Words: Bone, Index finger, Immunohistochemistry, MPNST.