OUTCOMES OF CONJUCTIVAL AUTOGRAFT IN THE RECONSTRUCTION OF SURGICAL OCULAR SURFACE DEFECTS USING FIBRIN GLUE, AN EIGHT YEAR FOLLOW-UP STUDY

International Journal of Innovative Medicine and Health Science, Vol. 4, 2015, 73-80

H.N.Sowbhagya, N. Manjunath, Kiran Kumar

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ABSTRACT

Importance: To assess the efficacy of conjunctival auto graft (CA) done using fibrin glue (FG) for the reconstruction of ocular surface defects caused by the excision of pterygia(recurrent), combined naevus of conjunctiva & maltoma of conjunctiva.

Objective: to study & assess the use of CA done using fibrin glue in:

1)    Reconstructing conjunctival defects & in postoperative cosmesis, and

2)    To find out the incidence of recurrences of the pathology & types of postoperative complications.

Design of the study: Prospective, interventional case series study, conducted from Jan 2006 to Dec 2014.

Setting: Institutional study, done at Kempegowda Institute of Medical Sciences, Bangalore.

Participants/Materials and methods: Ten eyes of nine patients who visited the outpatient department with various ocular surface disorders were selected randomly. All underwent CA done using fibrin glue (Reliseal) following surgical excision of the pathology. Eight eyes were of recurrent pterygium, one eye of malt lymphoma of size 12mm x 10mm & one case of combined naevus 8mm x 6mm. Follow up ranged from 3 to 8 years (Jan 2006 to Dec 2014).

Outcomes: All the cases showed good ocular surface reconstruction & showed no recurrences over the follow up period.

Results: Eight eyes having recurrent pterygium, satisfying the inclusion criteria underwent pterygium excision with CA using fibrin glue. One eye of malt lymphoma underwent CA with fibrin glue after total excision of the malt lymphoma, One case of combined naevus of limbus underwent total excision with CA using fibrin glue. Success was achieved in 100% of the cases with respect to prevention of recurrences & 90% with respect to cosmetic surface reconstruction.

Conclusion: CA done using fibrin glue resulted in the effective management of ocular surface defects following the excision of various conjunctival pathologies.

Keywords: conjunctival auto graft, recurrent pterygium, malt lymphoma, limbal combined naevus, fibrin glue.