Description

ABSTRACT

Background: The focus of the present study was to assess the in vitro antioxidant and free radical scavenging capacity of bioactive metabolites existing in Albizia lebbeck (L.) Benth leaf extract. Results: The IC50 values obtained in the antioxidant activity of different fractions from Albizia lebbeck was studied using DPPH, NO, SOD, LP, NSSDRD and SSDRD. The CF fraction demonstrated highest IC50 (μg/ml) value of 73.53 and lowest value of 25.02 was demonstrated by PE as evaluated by DPPH assay. Similar results were obtained for NO assay, where CF showed an activity of 60.46 and PE demonstrated an activity of 16.56. LP assay demonstrated highest activity for CF and lowest activity for AQ extract. Conclusions: The extract is a possible source of antioxidants/free radical scavengers consisting vital metabolites which can be connected to its ethno-medicinal use.

Keywords: Free radical scavengers, Albizia lebbeck, antioxidants, phytochemicals, bioactive constituents, extraction