Description

ABSTRACT

Asymptomatic bacteriuria in pregnancy is associated with an increased risk of pyelonephritis leading adverse effects as pre-term delivery and fetal loss. The study aims to determine the prevalence of asymptotic bacteriuria among HIV-positive pregnant women followed up in the “Centre de l’Appui Psycho-Médico-social (APMS)” of Ndjamena (Chad), and to identify the sensitive antibiotics against their urinary isolates. Seventy six followed up HIV-positive pregnant women who did not show any symptoms considered as urinary infection were involved after informed consents were obtained. Their socioeconomic conditions were determined using a semi-structured questionnaire. Having been taught the art of urine collection, a mid-stream urine specimen was taken and delivered onto agar Uriselect 4. Plated dishes were then incubated at 37°C overnight. After incubation, density of colonies was compared to a diagram to determine the number of cells per milliliter. Antibiotic sensitivity test were carried out using NCCLS discs diffusion method. The investigation revealed that 59.21% of subjects of the study population were in the age range of 25-34 years. The majority of them were married (69.74%), and 50% were multiparous. Regarding the occupation, 56.58% among participants were housewife. Asymptotic bacteriuria prevalence was 32.89% in the study population. E. coli had the highest value (56%) while Klebsiella pneumoniae, Enterobacter cloacae and  Staphylococcus aureus had lowest value of (8%) each respectively. Cefoperazone, Cefsulodine and Cefixime were recorded as the most effective antimicrobial against the urinary isolates.

Keywords: HIV-infected, Pregnant Women, Asymptomatic Bacteriuria, Urine Culture, Antibiogram.