Description

ABSTRACT

Background: Xerostomia is a common clinical problem, and different medications have been tried in its management. In the present study, herbal supplements like extract of ginger and orange peel are used to assess their effect on salivary quantity, salivary pH and buffering capacity. Aim: To evaluate and compare the efficacy of citric acid, extract of ginger and Orange peel oil mucoadhesive tablets as salivary stimulants in healthy volunteers. Objective: The main objective of study was to compare the quantity, pH and buffering capacity of saliva between inter and intra groups. Methodology: A total of 20healthy volunteers (aged 20-30) were selected. Mucoadhesive tablets of citric acid, ginger and orange peel extract was prepared. A 3 way cross over was done to assess the impact of the stimulants on salivary quantity, pH and buffering capacity at baseline, 10 minutes, 30 minutes and 60 minutes. Results: Comparisons between inter and intra groups using the (ANOVA test) showed that there was a significant increase in quantity of saliva , pH and buffering capacity after treatment for both ginger and orange peel mucoadhesive tablets. Conclusion: Ginger being an herbal product can be tried as a novel, reasonable and available treatment as salivary stimulant for symptomatic oral dryness.

Keywords: Saliva, Dry mouth, Ginger, Orange peel, Citric acid, Mucoadhesive tablets